Ronis ML, Harwich JD, Fung R, Dellavecchia M (1984) Review of cyanoacrylate tissue glues with emphasis on their otorhinolaryngological applications. Type IV hypersensitivity reactions following Dermabond adhesive utilization in knee surgery: A Report of Three Cases. 0000059447 00000 n ACD to topical skin adhesives usually presents as a self-limiting urticarial eruption near the incision site and subsides after proper local management. Spauwen, P. H., de Laat, W. A. A healthy 36-year-old white woman with a deflated silicone gelfilled breast implant underwent uneventful removal of her implants, bilateral capsulotomies, replacement of her implants with 325-cc silicone gelfilled implants, and bilateral mastopexies. 0000005379 00000 n I had a horrible reaction too. Parekh, Nirav N. Close-up view of erythema surrounding the right lower abdominal 5-mm trocar site on post-operative day 7. Emerg. Having any kind of surgery means being exposed to many materials and medications. White, Andrew A. On postoperative day one, she was seen routinely and was well. 3Handschel JG Depprich RA Dirksen Det al. 8600 Rockville Pike Shupak, Raymond P. Published reports of an allergic reaction to Dermabond, Time elapsed from surgery to onset of allergic reaction (days), Unreported; each with 1-3 prior orthopedic surgeries, Yes, 1-year prior for tubal ligation with haphazard application and prolonged embedded application, Octyl-2 cyanoacrylate and Prineo self-adhering mesh ++, Dermabond& 2-hydroxyethyl methacrylate +++, Dermabond & N-2-butyl cyanoacrylate +++, Neurosurgery, Laparoscopic General Surgery, None for first case & yes for other 3 cases, Dermabond, Dermabondwith chlorhexidine, and Dermabond with povidone iodine +++. The exclusion criteria included age<18years, inflammatory disease (e.g., rheumatoid arthritis or psoriatic arthritis), active infection in the area of incision prior to surgery, or follow-up of less than 6weeks. Problems with Dermabond are mostly related to application technique. Has data issue: false 0000007745 00000 n Figure 2. Hayes, Sharon Caskey (2004) Discovery of Super Glue helped land Coover in National Inventors Hall of Fame," Kingsport Times-News. Please enable it to take advantage of the complete set of features! Wright JD, Ananth CV, Lewin SN, Burke WM, Lu YS, et al. Post-surgery contact dermatitis is generally caused by an allergen or something that irritates your skin. The variables used to determine the risk factors of ACD to topical skin adhesives were retrieved from electronic medical records. Treatment is simple and most cases will resolve within a few weeks. After the surgical procedure of each patient, the fascia and subcutaneous layers were closed using 20 and 30 synthetic absorbable braided sutures. and Dermatitis 2016; 27 (2):75. We identified patients with positive patch test results for Dermabond and evaluated their results concerning (meth)acrylates and ethyl cyanoacrylate adhesive. Med. 0000060206 00000 n Allergy 64, 801806 (2009). It. Cell Mol. Plast. All data in this study are freely available to any researcher for noncommercial purposes. This polymerization is an exothermic reaction which may release significant heat [7]. Allergic reactions to 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, NJ) are rare in the medical literature; there is only one published report.1 There are, however, scattered anecdotal reports of allergies to Dermabond on the Internet. It took over three weeks to go away. This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department. As these values did not differ from those of all patients with possible risk factors (p=0.857 and 0.955, respectively), we concluded that previously known risk factors for type IV hypersensitivity did not significantly affect the incidence of ACD in topical skin adhesives. Providing cutting-edge scholarly communications Pamela L. Scheinman, Marc Vocanson, Ari M. Goldminz, Hyo-Eun Kwon, Hye-Jin Ahn, Min Kyung Shin, Stephan Weidinger, Lisa A. Beck, Alan D. Irvine, Young Jae Kim, Dong Jun Lim, Chong Hyun Won, Vasco Silva-Neves, Vitor Hugo, Miguel Pais-Vieira, Mario Mastrocola, Georg Matziolis, Henk Eijer, Julie Bruce, Blessing Oyedemi, Freya Harrison, Young-Je Kim, Mi Ji Choi, Beom Joon Kim, Raiyyan Aftab, Vikash H. Dodhia, Ryckie G. Wade, Scientific Reports A severe allergic reaction can be seen; erythema and pruritis are both present along the incisions where Dermabond was applied. In addition, the sutureless closure has become a marketing tool for surgeons. Quinn, J. et al. Complications associated with Dermabond during head and neck surgery: MAUDE and literature review. J. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. ANZ J. Surg. 2022. I also found that taking liquid Benedryl before bed really helped too. 2022 Mar-Apr;43(2):103330. doi: 10.1016/j.amjoto.2021.103330. The material is rapidly converted from a liquid to a solid state via polymerization at room temperature without the need for a catalyst, evaporation of a solvent or application of pressure [5]. There has never been a reported case resulting from gynaecologic surgery until now. A 63-year-old female presented on post-operative day 7 status post total laparoscopic hysterectomy and bilateral salpingo-oophorectomy with sudden onset erythema and pruritus around all four port site incisions. The distinction between infection and contact dermatitis is critical. H\n@C 3,9Fa} c/vMDZ$qvoxnS1>[yos,:? Article Our community is filled with women who have been through the Hysterectomy experience providing both advice and support from our active members and moderators. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. We report a case of a fulminant allergic reaction to Dermabond following a mastopexy. Dermabond has rapidly disseminated to nearly every surgical specialty due to the unique ease of use. Occupational asthma has also been linked to exposure to cyanoacrylate adhesives used to affix sculpted acrylic artificial nails in beauty salons [28]. Please enable it to take advantage of the complete set of features! Article 2021. Her husband, a physician, feared infection and prescribed 1 g of intramuscular ceftriaxone (Rocephin; Roche Laboratories, Nutley, NJ) and oral sulfamethoxazole/trimethoprim (Bactrim DS; Roche Laboratories). 2018. Singer AJ, Quinn JV, Hollander JE (2008) The cyanoacrylate topical skin adhesives. Thus, the increasingly large number of hysterectomies being performed with traditional laparoscopic and robotically-assisted laparoscopic techniques may contribute to a gross underestimation of the actual number accomplished. 0000002888 00000 n 0000056539 00000 n This relationship ended in 2005. Dermal Hypersensitivity Reaction to Semaglutide: Two Case Reports. An official website of the United States government. %PDF-1.7 % In fact, n-butyl cyanoacrylate is increasingly preferred for vascular embolization, bleeding hemostasis, or corneal injury repair over skin closure30,31,32. ~)4@ @ u~_/eo/Zi}M^_3AAgFqf Feature Flags: { However, in some patients, it mimics postoperative infection, causes severe local or systemic reactions, and eventually, cosmetic sequelae17. 0000010011 00000 n HysterSisters.com is a massive online community with over 475,000 members and over 5 million posts. Coover HW, Joyner FB, Shearer NH, Wicker TH (1959) Chemistry and performance of cyanoacrylate adhesives. Contact Dermatitis. Three days postoperatively, she reported erythema around her incisions. Of note, the patient underwent a tubal ligation one year before this procedure. Diffuse cutaneous allergic reaction to Dermabond - PubMed 0000059825 00000 n Key words sharing sensitive information, make sure youre on a federal 0000003512 00000 n 0000031623 00000 n Incidence and risk factor of allergic contact dermatitis to 2-octyl 2009 Jul-Aug;29(4):314-6. doi: 10.1016/j.asj.2009.02.019. (n.d.). 0000053601 00000 n Hysterectomy is the surgical removal of the uterus. The Bactrim DS was continued for one week because of the broken skin and the danger of superinfection. 15, 689695 (2004). Skin Wound Care 30, 272286 (2017). However, in this study, the use of topical skin adhesive did not differ by sex, and the incidence of ACD was also not affected by sex. For wound dehiscence, adhesive tape was applied to the margins of the wound. Her itching ceased within hours of these final treatments. PDF Allergic reaction to Dermabond in gynaecologic surgery - OAText This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. J. Arthroplasty 28, 553556 (2013). 0000008134 00000 n Aesthet Surg J. Anaphylactic allergic reaction, throat closure and systemic pruritus, has been noted following exposure to aspirin and codeine approximately 20 years prior. Technol. 2021 Mar 24;13(3):e14090. Similarly, when we analyzed the incidence of ACD in patients without risk factors for type IV hypersensitivity, as suggested in previous studies, the incidence of ACD was 2.5% (15/590) in 2-octyl cyanoacrylate and 2.2% (6/279) in n-butyl cyanoacrylate. 2014. 2020. Kanerva L, Lauerma A, Estlander T, Alanko K, Henriks-Eckerman ML, Jolanki R. Am J Contact Dermat.
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